Clinico-pathological aspects in hepatocellular carcinoma
نویسندگان
چکیده
Mocanu Elena, University Alley, 900437 Constanta, Romania e-mail: [email protected] ABSTRACT Hepatocellular carcinoma is one of the most common cancers and the age distribution of HCC patients has steadily increased because of the improved management of chronic liver diseases. The peak age of onset of hepatocellular carcinoma is continually increasing worlwide. This study aims to evaluate whether there exists any signifi cant diff erence in the clinicopathological features between youngerand elderly-HCC patients. Consecutive 40 patients who had undergone surgical resection for the treatment of HCC from January 2005 to December 2009 were enrolled in our study. Among patients studied, 7 were elderly-HCC and 33 were younger-HCC. Hepatocellular carcinoma was predominantly associated with chronic HBV-infection. Abdominal pain was the most frequently symptom and hepatomegaly was the most frequently sign of HCC in our study. Most patients presented elevated serum AFP levels. In elderly goup the most frequent Edmondson Steiner grading were poorly diff erentiated with 5 cases, while in young group were the same number, 15, of cases moderately and poorly diff erentiated.
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